You can. It works fine if you know the limitations. An important one is, drives could disconnect, so traditional RAID wouldn't be good.

If you want redundancy, look at something like SnapRAID, http://www.snapraid.it

If you want to combine into a single volume, consider rclone. These remotes specifically are the ones I'm thinking could be useful,

- https://rclone.org/local/

- https://rclone.org/combine/

- https://rclone.org/cache/

Good luck o7