> Ivermectin (IVM) [...] exhibits low oral bioavailability

Low oral bioavailability must be upsetting news for anyone who gagged down tubes of horse paste in the last few years

> blood-brain barrier

Sounds like the key use of IVM here is that it crosses the blood-brain barrier and can carry medicines into brain tissue where cancers are otherwise hard to treat?

https://translationalneurodegeneration.biomedcentral.com/art... (open access)

Well some claim that up to 98% of oral meds don't cross the bbb so this increases the candidate list 50x