you certainly can. Omarchy doesn't appear to be anything special, just a tiling WM (of which there are plenty of on macOS: aerospace, yabai, amethyst, etc.) with some preinstalled applications + basic dotfiles. people have been running similar setups for years on macOS
Are you aware that Omarchy is just a bunch of scripts on top of a GNU/Linux distro, which has been available in one way or another for the past three decades?
