what for? sugar is already broken down in your body into glucose to be absorbed. there are already enzymes you can take to help break it down faster, but it's all going to be absorbed regardless.
perhaps what you really want is something to block glucose absorption?
You could invent resistant bacteria that eats all the sugar in your stomach. There are already such but they are lethal if you don't do much about them, but maybe it is possible to make nice versions of them that just eats sugar and don't kill you
by eating everything.
perhaps what you really want is something to block glucose absorption?