For Python, I'd encourage you to look at the BeeWare suite. BeeWare allows you to write GUI's once and build for desktop and mobile (and eventually, web, again). It's still writing a GUI instead of working visually, but for basic to intermediate apps, you don't have to get into the nitty gritty of UI design, know anything about Qt (wooooo), and build a nice, capable GUI app.

https://beeware.org/