Recently I looked into this subject and talked with a postdoc researcher. It is interesting to see this discussion on HN.
C elegans is far more complicated than the connectome abstraction used in these projects. There are all kinds of ion channels, including new ones recently discovered (https://pubmed.ncbi.nlm.nih.gov/34388373/ ), that are regulated by genes and other physical/biochemical factors in the body that are very poorly understood. We only have slightly better understanding of its brain development recently ( https://www.nature.com/articles/s41586-021-03778-8 ). The in vivo research on C. elegans neural system mostly uses the concentration of Ca+ as the neuron activity indicator, which lefts out other details.
According to the postdoc that I talked with, we are still very very far from even accurately understanding a single neuron, let alone simulating any neural network completely.
C elegans is far more complicated than the connectome abstraction used in these projects. There are all kinds of ion channels, including new ones recently discovered (https://pubmed.ncbi.nlm.nih.gov/34388373/ ), that are regulated by genes and other physical/biochemical factors in the body that are very poorly understood. We only have slightly better understanding of its brain development recently ( https://www.nature.com/articles/s41586-021-03778-8 ). The in vivo research on C. elegans neural system mostly uses the concentration of Ca+ as the neuron activity indicator, which lefts out other details.
According to the postdoc that I talked with, we are still very very far from even accurately understanding a single neuron, let alone simulating any neural network completely.
Edit: typo