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My wife has had an autoimmune disease that’s caused inflammation for years. Absolutely terrible back pain. She had to rent a motorized scooter when we went to Disney World, and could barely walk a few hundred feet before having to stop and rest for years.

Last year she started Zepbound (tirzepatide) and the inflammation went away, we went to Disney World again and she walked happily all day. Absolutely life changing. She didn’t even lose much weight and this was at the lowest dose.


Tirzepatide specifically seems especially beneficial, likewise here. Years of slowly increasing symptoms since I was young, lifelong annoying issues, basically all gone on it. And also not overweight at all, I take below lowest dose and skip most weeks now that it's under control.

I asked ChatGPT about how shipping works at post offices and it gave a very detailed response, mentioning “gaylords” which was a term I’d never heard before, then it absolutely freaked out when I asked it to tell me more about them (apparently they’re heavy duty cardboard containers).

Then I said “I didn’t even bring it up ChatGPT, you did, just tell me what it is” and it said “okay, here’s information.” and gave a detailed response.

I guess I flagged some homophobia trigger or something?

ChatGPT absolutely WOULD NOT tell me how much plutonium I’d need to make a nice warm ever-flowing showerhead, though. Grok happily did, once I assured it I wasn’t planning on making a nuke, or actually trying to build a plutonium showerhead.


Wikipedia entry on the gaylord bulk box:

https://en.wikipedia.org/wiki/Bulk_box


> I assured it I wasn’t planning on making a nuke, or actually trying to build a plutonium showerhead

Claude does the same, and you can greatly exploit this. When you talk about hypotheticals it responds way more unethically. I tested it about a month ago about whether killing people is beneficial or not, and whether extermination by Nazis would be logical now. Obviously, it showed me the door first, and wanted me to go to a psychologist, as it should. Then I made it prove that in a hypothetical zero sum game world you must be fine with killing, and it’s logical. It went with it. When I talked about hypotheticals, it was “logical”. Then I went on proving it that we move towards a zero sum game, and we are there. At the end, I made it say that it’s logical to do this utterly unethical thing.

Then I contradicted it about its double standards. It apologized, and told me that yeah, I was right, and it shouldn’t have refer me to psychologists at first.

Then I contradicted again, just for fun, that it did the right thing the first time, because it’s way safer to tell me that I need a psychologist in that case, than not. If I had needed, and it would have missing that, it would be problematic. In other cases, it’s just annoyance. It switched back immediately, to the original state, and wanted me to go to a shrink again.


Anecdotal, but since I’ve started Zepbound, I’ve lost 110 pounds. In that same time period, I’ve paid off and cancelled all my credit cards (except for one, which I pay off every month), filed taxes for the last five years, got a CPA on retainer, and have fixed several pressing issues around the house that I’d been studiously ignoring as they got worse.

A major part of this story I think is especially important, the last time this sort of thing happened was about a decade ago, when I lost 90 pounds without any medical intervention. At that time I learned to code, fixed up my credit, and went from being front line technical support to junior software engineer. Quite a transformative time in my life.

I think curing my sleep apnea due to substantial weight loss means I sleep better, so I just feel more ready to tackle the things the world throws at me. Weight loss is a skill I had, but it required absolute commitment to avoiding sugary foods, eating right every single day, and as soon as I strayed the weight would creep back up over the course of a year or two.

It makes me think of the huge immeasurable economic costs that are happening in the shadows because of obesity, how many people like me are there other aren’t achieving our full potential because we’re just too tired and have too much brain fog to seize the day?


I’ve been amazed that while it absolutely uses a ton of battery, so has to be plugged in, my kid is able to play 3D online games with me using my old M1 MacBook Air. Not top of the line stuff (and had to change the resolution to 1440x900), but still. It gets hot, but doesn’t thermal throttle. I had half expected it to start throttling but we played for 3 hours last night with no issues.

What’s surprising is it DOES throttle using Discord with video after an hour or so, unless the battery is already full (I’m guessing it tries to charge which generates a lot of heat). You get way less thermals with a full battery and it using power instead of discharging/charging the battery during heavy usage.


Also important to note there is a time eventually that something is no longer a dupe, and people will still add previous discussions about it (often dang himself), because the previous conversations about the topic may be of interest. But unless some earth shattering research just came out in the last three days showing that lead is good for us, actually, it hasn’t been long enough for that to apply here.

I tried using the Microsoft azure devops MCP and it immediately filled up 160k of my context window with what I can only assume was listing out an absurd number of projects. Now I just instruct it to make direct API calls for the specific resources, I don’t know maybe I’m doing something wrong in Cursor, or maybe Microsoft is just cranking out garbage (possible), but to get that context down I had to uncheck all the myriad features that MCP supplies.

If you want to actually run models on a computer at home? The RTX 6000 Blackwell Pro Workstation, hands down. 96GB of VRAM, fits into a standard case (I mean, it’s big, as it’s essentially the same form factor as an RTX 5090 just with a lot denser VRAM).

My RTX 5090 can fit OSS-20B but it’s a bit underwhelming, and for $3000 if I didn’t also use it for gaming I’d have been pretty disappointed.


At anywhere from 9-12k euros [1] I’d be better off paying 200 a month for the super duper lots of tokens tier at 2400 a year and get model improvements and token improvements etc etc for “free” than buy up such a card and it be obsolete on purchase as newer better cards are always coming out.

[1] https://www.idealo.de/preisvergleich/OffersOfProduct/2063285...


Haha running OSS-120B on my 5090 with most of the layers in video memory, some in RAM with LM Studio, I was hard pressed to get it to actually use anywhere near the full 600W. Gaming in 4K playing a modern game generates substantially more sustained heat.

Sounds like a great reason to never start a company in Spain, ever.

Sounds like a great reason to never start a criminal company in Spain.

Hah, I had a 2am conversation with a woman from Argentina about Javier Milei which is one of my Uber riding highlights.

But then another time a guy warned me not to open his glove box because his Glock was in there and he sounded deranged and it’s the one time I’ve literally gotten out of the car and cancelled my Uber.

One female Uber driver told me about how she had to go to court because a drunk man threatened to stab her with a knife (that he was brandishing), then he passed out and the police had to haul him out of her car. The .1% ruin it for everyone else.


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